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AI Tools for Physician Assistants
AI tools for clinical decision support, drug interaction checking, clinical trial discovery, diagnostic research, and evidence-based patient documentation.
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Drug pairSeverityMechanism
Lisinopril + MetoprololLowAdditive BP lowering
Atorvastatin + AspirinNoneNo interaction
Lisinopril + Aspirin (>100mg)ModerateNSAIDs reduce ACE-I efficacy
No major interactions detected · regimen compatible
Medication safety verification
Before prescribing or adjusting medications, verify contraindications, side effects, and drug interactions against a patient's full medication list. Catch potential safety issues instantly.
Check interactions for a 68-year-old starting sertraline 50mg. Current meds: warfarin 5mg, atenolol 25mg, amlodipine 5mg, prednisone 10mg (taper). Any concerns?
Sertraline + warfarin: SIGNIFICANT interaction (increased bleeding risk). INR monitoring essential. Sertraline + atenolol: minor (additive bradycardia possible). Prednisone: okay. Recommendation: start sertraline, increase INR monitoring frequency, counsel on bleeding signs.
ToolRouter lookup_drug
Sertraline + Warfarin
SIGNIFICANT — increased bleeding risk · increase INR monitoring
Sertraline + Atenolol
Minor — additive bradycardia possible · monitor pulse
Sertraline + Amlodipine
No significant interaction
Sertraline + Prednisone
No significant interaction
Recommendation
Start sertraline · increase INR frequency · counsel on bleeding signs
Clinical trial matching and referral
Identify clinical trials matching patients' diagnoses and demographics. Empower patients with access to cutting-edge treatments while supporting research advancement.
Find clinical trials for a 72-year-old with newly diagnosed Alzheimer's disease (mild cognitive impairment stage). Interested in novel disease-modifying therapies.
Found 4 recruiting trials for early Alzheimer's: 2 testing monoclonal antibodies targeting amyloid/tau, 1 on cognitive training with biotech combo, 1 on exercise intervention. Nearest site: 25 miles. All accepting MCI stage patients.
ToolRouter search_trials
TrialInterventionPhase
CLARITY AD ExtensionLecanemab — amyloid antibodyPhase 3
TRAILBLAZER-ALZ 3Donanemab — tau/amyloid comboPhase 3
MCI + Exercise RCTStructured aerobic + cognitive trainingPhase 2
4 recruiting trials · all accepting MCI stage patients
Diagnostic support and differential development
Build comprehensive differential diagnoses with supporting clinical evidence. Research diagnostic criteria, red flags, and workup recommendations for complex presentations.
Build a differential diagnosis for a 45-year-old with progressive dyspnea, fatigue, and lower extremity edema. What's the diagnostic workup?
Top differentials: heart failure (most likely given symptom cluster), nephrotic syndrome, cirrhosis, severe anemia. Recommended workup: ECG, BNP, echocardiography, basic metabolic panel, urinalysis, albumin. Recent evidence emphasizes BNP as first-line test. See attached research.
ToolRouter research
Top Differential: Heart Failure
Most likely given symptom cluster — BNP + echo
Differential: Nephrotic Syndrome
Urinalysis + albumin — edema without JVD
Differential: Cirrhosis
LFTs + albumin — check for hepatomegaly
Differential: Severe Anemia
CBC — fatigue + dyspnea on exertion
First-Line Workup
ECG · BNP · echo · BMP · UA · albumin
ToolRouter search_papers
Sensitivity
93% for HF diagnosis (NEJM 2002)
Specificity
74% — supports rule-in with clinical context
Recent Meta-Analysis
BNP <100 pg/mL virtually excludes HF (Lancet 2024)
Ready-to-use prompts
Drug interaction check
Check for interactions between ciprofloxacin 500mg BID, metformin 1000mg BID, lisinopril 20mg daily, and the patient also wants to take cranberry supplements. Any concerns?
Clinical trial search
Find recruiting clinical trials for a 52-year-old with hypertension-resistant to 3 medications (amlodipine, lisinopril, hydrochlorothiazide). Interested in new drug classes or interventions.
Diagnostic research
Compile diagnostic criteria, epidemiology, clinical features, and red flags for tension headache vs. migraine vs. cluster headache. How to differentiate?
Evidence review
Search for recent studies on the efficacy of physical therapy vs. corticosteroid injections for shoulder impingement syndrome. What does the evidence say?
Tools to power your best work
Deep ResearchAI research reports with citations
Drug InformationDrug info: recalls & side effects
Clinical TrialsClinical trials & drug safety data
165+ tools.
One conversation.
Everything physician assistants need from AI, connected to the assistant you already use. No extra apps, no switching tabs.
New symptom evaluation
When evaluating a patient with new or worsening symptoms, develop differentials, find clinical evidence, and identify diagnostic workup.
Medication adjustment and safety check
When starting or adjusting medications, verify safety, check interactions, and research alternatives if concerns identified.
Frequently Asked Questions
Should I rely on drug interaction checking alone for prescribing decisions?
No. This tool is a clinical support tool that highlights potential interactions. Always review full prescribing information, consult with pharmacy if available, and apply clinical judgment. Interactions vary by dose, duration, and patient factors.
How do I talk to patients about clinical trials?
Use trial information to present options as an opportunity to access cutting-edge treatments while contributing to medical research. Discuss potential benefits, risks, time commitment, and randomization. Provide trial contact information for patient questions.
Can I use this research to develop clinical guidelines locally?
Yes. The research and evidence tools provide a strong foundation for developing local protocols. Combine this evidence with institutional guidelines, expert consensus, and your patient population characteristics.
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