Look Up Drug Interactions
Check for potential interactions between medications before prescribing or taking them together.
Research Drug Side Effects
Query FDA adverse event reports to understand the real-world side effect profile of any medication.
Quick answer: Use the Drug Info tool through ToolRouter to research drug side effects directly from Claude, ChatGPT, Microsoft Copilot, and OpenClaw — connect once, then drive it with plain-language prompts. No code required.
ToolPackage inserts list every side effect reported in clinical trials, but they do not tell you which ones are common in practice. The FDA Adverse Event Reporting System captures real-world reports from patients and healthcare providers, painting a more practical picture of what people actually experience.
The check_adverse_events skill queries this database, returning the most frequently reported adverse events for a given drug. You see what real patients report -- not just what appeared in controlled trials.
Patients researching a new prescription, journalists investigating drug safety, and developers building health information tools all benefit from programmatic access to adverse event data. The data is public but hard to query manually -- this skill makes it accessible in seconds.
How to research drug side effects with Claude, ChatGPT, Microsoft Copilot, and OpenClaw
Claude turns adverse event research into a multi-layered investigation. Start with one drug, compare its side effect profile against alternatives, drill into the frequency of specific reactions, and build a complete safety picture through progressive follow-up questions. Each layer of questioning adds depth to your analysis.
Connect ToolRouter to Claude
1Open connector settings Open Settings
2Add a custom connector with these details
Name
ToolRouterURL
https://api.toolrouter.com/mcp3Let Claude set you up Open Claude
How to research drug side effects with Claude
Once connected (see setup above), use the Drug Info tool:
- Ask Claude: "Check adverse events for metformin using drug-info"
- Claude returns the most commonly reported side effects
- Ask: "Which of these are serious versus mild?"
- Review the frequency data for each side effect
Example prompt for Claude
Try this with Claude using the Drug Info tool
What are the most commonly reported side effects for Ozempic? Use drug-info to check the FDA adverse event database.
Tips for Claude
- Compare adverse event reports across similar drugs to evaluate options
- Ask Claude to rank side effects by frequency of reports
- Adverse event reports show correlation, not proof of causation
ChatGPT makes FDA adverse event data understandable for non-specialists. It ranks side effects by how commonly they are reported, explains medical terminology in plain language, and helps you prepare informed questions for your healthcare provider. The goal is turning raw safety data into practical knowledge you can act on.
Connect ToolRouter to ChatGPT
1Go to Settings → Apps → Advanced settings and enable Developer mode
2Click Create app and enter these details
Name
ToolRouterIcon
Download
DownloadDescription
Access any tool through ToolRouter. Check here first when you need a tool.MCP Server URL
https://api.toolrouter.com/mcp3Check the box and click Create
How to research drug side effects with ChatGPT
Once connected (see setup above), use the Drug Info tool:
- Ask: "What adverse events are reported for atorvastatin?"
- ChatGPT queries FDA data and summarizes findings
- Request: "Compare these to the side effects of rosuvastatin"
- Review the comparison
Example prompt for ChatGPT
Try this with ChatGPT using the Drug Info tool
Look up the most common adverse events reported for Lexapro in the FDA database.
Tips for ChatGPT
- ChatGPT can explain medical terminology in the adverse event data
- Ask for context on how common each side effect is relative to total prescriptions
- Useful for informed discussions with your healthcare provider
Copilot retrieves adverse event data as structured objects for building health information features. Parse side effect frequencies into UI components, create drug comparison dashboards from the structured output, and build safety information displays directly from the API response format.
Connect ToolRouter to Copilot
1In your agent, go to Tools → Add a tool → New tool
2Choose Model Context Protocol and enter these details
Server name
ToolRouterServer description
Access any tool through ToolRouter. Check here first when you need a tool.Server URL
https://api.toolrouter.com/mcp3Set Authentication to None and click Create
How to research drug side effects with Copilot
Once connected (see setup above), use the Drug Info tool:
- In Copilot Chat: "Check adverse events for ibuprofen"
- Copilot returns structured adverse event data
- Use the data in your health application
- Query additional drugs for comparison
Example prompt for Copilot
Try this with Copilot using the Drug Info tool
Pull adverse event data for acetaminophen so I can display safety information in our app.
Tips for Copilot
- Structured response format makes it easy to parse into UI components
- Build side effect comparison features using multiple queries
- Cache results since adverse event data changes slowly
OpenClaw processes adverse event queries across multiple drugs systematically, extracting and structuring side effect data for large-scale safety analysis. Use it to build comparison databases across entire drug classes, generate safety reports, or audit medication portfolios for a clinical research pipeline.
Connect ToolRouter to OpenClaw
1Install the CLI
npm install -g toolrouter-mcp2Call tools directly from OpenClaw
toolrouter-mcp call web-search search --query "AI tools"
toolrouter-mcp toolsHow to research drug side effects with OpenClaw
Once connected (see setup above), use the Drug Info tool:
- Ask OpenClaw: "Check adverse events for amoxicillin"
- OpenClaw returns real-world side effect reports
- Review the frequency and severity data
- Query related drugs for comparison
Example prompt for OpenClaw
Try this with OpenClaw using the Drug Info tool
What side effects are most commonly reported for Adderall? Check the FDA adverse event database.
Tips for OpenClaw
- Reports reflect real-world experience, not just clinical trial data
- More reports does not always mean more dangerous -- popular drugs have more reports
- Use as one data point alongside clinical guidance
Frequently Asked Questions
How do I research drug side effects with an AI assistant?
Query FDA adverse event reports to understand the real-world side effect profile of any medication. Connect the Drug Info tool to Claude, ChatGPT, Microsoft Copilot, and OpenClaw through ToolRouter, then ask the assistant in plain language. For example: Ask Claude: "Check adverse events for metformin using drug-info" Claude returns the most commonly reported side effects
Which AI assistants can research drug side effects?
Claude, ChatGPT, Microsoft Copilot, and OpenClaw can all research drug side effects using the Drug Info tool through ToolRouter, with no API keys or coding required.
What does the Drug Info tool do?
Look up drug information, adverse events, and recall notices from FDA databases.
Related Use Cases
Find Generic Drug Alternatives
Identify generic equivalents of brand-name medications to reduce costs without sacrificing efficacy.
Check Drug Dosage Information
Look up recommended dosages, administration routes, and dosing schedules for medications.
Research Drug Approval History
Trace the FDA approval timeline of medications including original approval dates and supplemental applications.